How is pig isulin different from human insulin? why did associates hold allergic reaction to pig insulin?

Answers: Pig and human insulin, for example, differ in one amino sour, namely the carboxy-terminal amino acid of the so-called B-chain. This so-called B30 amino bitter is alanine in pig insulin but threonine within the human. Pig insulin could therefore be converted into human insulin by replacing this B30 amino tart by threonine and a number of methods are certain for doing so.

Insulin allergy and lipoatrophy in type 1 diabetic patients hold been previously reported but the mechanism are not well documented